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DTSTAMP:20260904T225238Z
SUMMARY:The genetic basis of animal domestication - a walk in the footsteps
  of Charles Darwin
DESCRIPTION:Charles Darwin used our domestic animals as proof-of-principle 
 for evolution by natural selection. He argued that this is a very similar 
 process to the one that occurs in our domestic animals due to selective br
 eeding. In fact\, Darwin himself made breeding experiments to prove this. 
 During the 1980s I got the vision that the development of new molecular ge
 netic methods now will allow us to reveal which genetic changes have been 
 critical for the development of our domestic animals. In this lecture I wi
 ll present some fascinating mutations that we have discovered and that hav
 e contributed to this process. This will include the specific mutation tha
 t explains variation in gait among horses. I will also discuss why the col
 our of our domestic animals changed and why Gandalf’s horse became white
 . Tameness is the most characteristic feature of all domestic animals and 
 I will also show how we used the rabbit to study the genetic changes that 
 were needed to transform an alert wild rabbit with a very strong flight re
 sponse into a docile domestic rabbit with a blunted flight response. Charl
 es Darwin started by observing biodiversity in nature during his voyage ar
 ound the globe on Beagle\, formulated his theory of evolution by natural s
 election and used domestic animals to collect evidence supporting his cont
 roversial theory. My scientific journey has gone in the opposite direction
 . For many years I have used domestic animals as models to understand the 
 genetic basis underlying evolutionary change. But in recent years\, thanks
  to the development of cost-effective methods for whole genome DNA sequenc
 ing\, I have expanded my research into wild animals. I will therefore end 
 by explaining what we have learned by sequencing the entire genome of all 
 species of Darwin’s finches on the Galapagos. by Prof. Leif Andersson\, 
 Department of Medical Biochemistry and Microbiology\, Uppsala University\,
  Sweden
DTSTART;TZID=Europe/Berlin:20180524T190000
DTEND;TZID=Europe/Berlin:20180524T000000
LOCATION:Ludwig-Erhard-Allee 2 \, Bonn (Deutschland) 
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DESCRIPTION:The genetic basis of animal domestication - a walk in the foots
 teps of Charles Darwin
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